Keratocystic odontogenic tumor related to nevoid basal cell carcinoma syndrome: clinicopathological study

  • Luana Eschholz Bomfin
  • Ana Paula M. Vivas
  • Andre Caroli Rocha
  • Maria Isabel W. Achatz
  • Clovis Antonio L. Pinto
  • Fabio Abreu Alves

Abstract

Aim: To assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with nevoid basal cell carcinoma syndrome (NBCCS) in a single Brazilian institution. Methods: After histopathological analyses of KCOT related to NBCCS, the medical charts of 14 patients were assessed. These patients presented a total of 31 primary and 8 recurrent KCOT. Results: Out of 14 patients, 8 presented a single KCOT, 4 showed synchronous tumors, 1 had 3 metachronous lesions and another patient had 2 synchronous lesions at initial evaluation and then developed other 3 metachronous lesions. Besides the 31 primary KCOTs, 18 lesions were located in mandible and 13 in maxilla. Most tumors presented unilocular pattern and association with a tooth. Conclusions: KCOT is a frequent manifestation of NBCCS and can be its first sign, mainly in young patients. In contrast to a previously published series, most patients presented a single lesion.

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Published
2016-12-12
How to Cite
BOMFIN, Luana Eschholz et al. Keratocystic odontogenic tumor related to nevoid basal cell carcinoma syndrome: clinicopathological study. Brazilian Journal of Oral Sciences, [S.l.], p. 23-29, dec. 2016. ISSN 1677-3225. Available at: <https://www.fop.unicamp.br/bjos/index.php/bjos/article/view/389>. Date accessed: 17 july 2019.
Section
Original Research