uec fopFaculdade de Odontologia de Piracicaba

Coordenadoria de Pós-Graduação



marcio lopesProfesor Titular del Departamento de Diagnóstico Oral, de la Facultad de Odontología de Piracicaba-UNICAMP.


  • Cirujano-dentista (1990), de la Facultad de Odontología de Piracicaba, Universidad Estatal de Campinas;
  • Maestro (1993), en Biología y Patología Buco-Dental de la Universidad Estatal de Campinas;
  • Doctor (1996), en Biología y Patología Buco-Dental de la Universidad Estatal de Campinas;
  • Post-Doctorado (1998-2000), em la Dental School University of Maryland USA.


  • Side effects in patients undergoing oncologic treatment, mainly radiotherapy and chemotherapy.
  • Efectos colaterales de pacientes en tratamiento oncológico, principalmente radioterapia e quimioterapia.
  • Prevención y diagnóstico de cáncer bucal
  • Diagnóstico de lesiones bucales
  • Pacientes jóvenes con cáncer bucal
  • Pacientes con leucoplasia verrucosa proliferativa


  • Feio PS, Gouvêa AF, Jorge J, Lopes MA. Oral adverse reactions after injection of cosmetic fillers: report of three cases. Int J Oral Maxillofac Surg. 2012 Jun 28. [Epub ahead of print]
  • Fonseca FP, Ramos LM, Vargas PA, de Almeida OP, Lopes MA, Santos-Silva AR. Oral adenosquamous carcinoma: evidence that it arises from the surface mucosal epithelium. Histopathology. 2012 Aug;61(2):321-3. doi:10.1111/j.1365-2559.2012.04257.x.
  • González-Arriagada WA, Santos-Silva AR, Ito FA, Vargas PA, Speight PM, Bingle L, Lopes MA. Expression pattern of PLUNC proteins as an auxiliary tool for the diagnosis of high-grade mucoepidermoid carcinoma of the salivary gland. J Oral Pathol Med. 2012 Apr 5. doi: 10.1111/j.1600-0714.2012.01145.x. [Epub ahead of print] PubMed PMID: 22487508.
  • Bitu CC, Carrera M, Lopes MA, Kowalski LP, Soares FA, Coletta RD. HOXB7 expression is a prognostic factor for oral squamous cell carcinoma. Histopathology. 2012 Mar;60(4):662-5. doi: 10.1111/j.1365-2559.2011.04102.x.
  • Hopp RN, Marchi MT, Kellermann MG, Rizo VH, Lopes MA, Jorge J. Lymphoma mimicking a dental periapical lesion. Leuk Lymphoma. 2012 May;53(5):1008-10.
  • Gouvêa AF, Ribeiro AC, León JE, Carlos R, de Almeida OP, Lopes MA. Head and neck amyloidosis: clinicopathological features and immunohistochemical analysis of 14 cases. J Oral Pathol Med. 2012 Feb;41(2):178-85.
  • Pinto LSS, Aguiar Júnior, FCA, Kowalski LP, Graner E. FAS and ErbB2 expression in early local recurrent oral cancer. Journal of Oral Pathology & Medicine 39: 176-181, 2010.
  • Gouvêa AF, Vargas PA, Coletta RD, Jorge J, Lopes MA. Clinicopathological features and immunohistochemical expression of p53, Ki67, Mcm-2 and Mcm-5 in proliferative verrucous leukoplakia. Journal of Oral Pathology & Medicine 39: 447-452, 2010.
  • Ito FA, Ito K, Coletta RD, Graner E, Almeida OP, Lopes MA. Salivary gland tumors: immunohistochemical study of EDG, EDFR, ErbB-2, Fatty Acid Synthase and Ki-67. Analytical and Quantitative Cytology and Histology 31: 280-287, 2009.
  • Silva ARS, Alves FA, Antunes A, de Góes MF, Lopes MA. Patterns of demineralization and dentin reaction in radiation-related caries. Caries Research 43: 43-49, 2009.
  • Kellermann MG, Sobral LM, Silva SD, Zecchin KG, Graner E, Lopes MA, Kowalski LP, Coletta RD. Mutual paracrine effects of oral squamous cell carcinoma cells and normal oral fibroblasts: induction of fibroblast to myofibroblast transdifferentiation and modulation of tumor cell proliferation. Oral Oncol 44: 509-17, 2008.
  • Kellermann MG, Sobral LM, Silva SD, Zecchin KG, Graner E, Lopes MA, Nishimoto I, Kowalski LP, Coletta RD. Myofibroblasts in the stroma of oral squamous cell carcinoma are associated with poor prognosis. Histopathology  51: 849-53, 2007.
  • Ito FA, Ito K, Vargas PA, Almeida OP, Lopes, MA. Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases. International Journal of Oral and Maxillofacial Surgery 34:  533-6, 2005.
  • Pires FR, Miranda A, Cardoso ES, Cardoso, Fregnani ER, Pereira CM, Correa ME, Almeida JP, Alves FA, Lopes MA, Almeida OP. Oral avascular bone necrosis associated with chemotherapy and biphosphonate therapy. Oral Dis 11: 365-9, 2005.
  • Silva SD, Agostini M, Nishimoto I, Coletta RD, Alves FA, Lopes MA, Kowalski L P, Graner E. Expression of fatty acid synthase, c-erbB2 and Ki67 in head and neck squamous cell carcinoma. Oral Oncology 40:  688 – 696, 2004.
  • Nikitakis N, Rivera H, Lopes MA, Siavash H, Reynolds MA, Ord RA, Sauk JJ. Immunohistochemical expression of angiogenesis-related markers in oral squamous cell carcinomas with multiple lymph nodes. American Journal of Clinical Pathology 119: 574 – 586, 2003.
  • Takahama Jr A, Alves FA, Pinto CAL, Carvalho AL, Kowalski LP, Lopes MA. Clinicopathological and immunohistochemical analysis of 25 head and neck osteosarcomas. Oral Oncology 39: 521 – 530, 2003.
  • Lopes MA, Nikitakis NG, Reynolds MA, Ord RA, Sauk JJ. Biomarkers predictive for lymph node metastases in oral squamous cell carcinoma. JOMS 60: 142-7, 2002.
  • Nikitakis N, Hebert C, Lopes MA, Reynolds MA, Sauk JJ. PPARg-mediated antineoplastic effect of nsaid sulindac on human oral squamous cell carcinoma cells. Int Journal of Cancer 98:  817 – 823, 2002.
  • Lopes MA, Nikitakis NG, Ord RA, Sauk JJ. Amplification and protein expression of 12q13-15 genes in osteosarcomas of the jaws. Oral Oncol 37: 566-571, 2001.
  • Lopes MA, Santos GC, Kowalski PL, Almeida OP. A clinicopathological study of 196 intraoral minor salivary gland tumors. J Oral Pathol Med 28: 264-267, 1999.

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